I think that just depends on your DVD drive.
I have a samsung, and I can run evox by itself off a CD-R.
I think one of the methods to get your xbox to read a disc better is to make the disc at least 1 gig or something.. (obviously you'd have to use a DVD at that point.)
I've never flashed a X2Lite, but I'm guessing it's really easy to do with Evox. Do you have the ability to load EvoX?
Otherwise, I'm unfamiliar with how to do it from a disc.