Gabriel Knight 2: The Beast WithinI wouldn't have hoped to dream about it, but the GK2 also works on Dosxbox V9, almost full speed (even the videos) and only with a few slight sound stutters once and a while. That said, I havent tested if and how changing CD's works and won't be able to for some time.
Also the game has the exact same problem as it's predecessor: Once you use the thumbstick for mouse emulation, the game crashes, so you won't be able to play it without a USB-adapter and a mouse.
Installation:
- Put the first CD in and start install.exe (make sure it is the GK2 install exe and not one of your previous games (by deleting the savegame for INSTALL.EXE from the dosxbox savegame folder (f.e. by using the emulators utilities option, or simly via ftp or an explorer app)))
- If it doesn't start, be sure to navigate to the DVD drive in dosxbox (by typing D: in the DOS console) and start it from there (by typing install)
- Install the game (I used the installation that took up the most space) with default settings
- Type in GK2DOS to run GK2DOS.bat
- The game should start
- Exit to the menu and search for the newly created GK2DOS.bat (you should find it in the dosxbox folder under "dosfiles") and add it to you favourites (optionaly

).
- Try to start it once more (Cycles 4000 (haven't tried any other settings yet), 16MB RAM)
- If it starts, congrats! If it gives you an error message about not being able to locate the sierra folder, exit dosxbox and move the GK2DOS.bat file from */SIERRA/GK2DOS.bat to */GK2DOS.bat ((*=what ever place the Sierra folder is located on your HDD) you might as well copy it, as the *.bat isn't that big

). Once you're done with that, launch dosxbox again and navigate to utilities/savegame manager. Delete the existing save for GK2DOS.bat. Launch the *.bat from its new location (you might add it to your favourites) and keep your fingers crossed.
Visual Performance-Tweaks:
Using bilinear filtering (click on the right thumbstick while the game is running and navigate to video options) makes the movies look a whole lot better, so you should use it. That said, once I switched from point to biliniar and exited the game, the next time I started the *.bat file, the emu crashed while launching the game. If this happens to you too, start the *.bat, hit the right thumbstick while the DOS console is on screen and switch back to Point Filtering. Once the game loads (and you see the Sierra logo) switch back to bilinear. Repeat on every launch.

hf
harlekin
edit:
I uploaded a few screencaptures just for the sake of it..
Gabriel Knight 2: The Beast Within on DosXbox V9