Yes, either the controls would need to be remapped to the contorller or either add support for keyboard and mouse, (controller)
I have not played this game yet so I wouldn't know what all the functions and screens would be.
I would vote for Keyboard and mouse support.
I'm been dying to test out my Codejunkie's keyboard for the last few weeks.
Going to have to install linux to play with it
![tongue.gif](http://forums.xboxscene.org/html/emoticons/tongue.gif)