Error 16 is a Dashboard error.
If you have the latest slayers and you've completely wiped the C:\ drive and replaced it with the files from System\C on Slayers, then your problem may be on the E:\ drive.
You should have E:\CACHE, E:\UDATA, E:\TDATA on this drive, I think Slayers has a blank E Drive set of files, rename your existing directories on E:\ and copy in the fresh ones from Slayers.
Once you've done all this you should be back to stock and it should boot the MSDash without errors, if you have an exploitable Game (007/MS/SC), then take the correct Krayzie nDure set of files an put them into E:\UDATA\, if not then look for the nDure for PC setup to make a set of C: & E: drive files to get the exploit running.
Just make sure you can get back to stock first, or the installers/exploits will run into problems.