If a soldered connection is done the right way, it should always work.
If your wires are oxidated, the solder will refuse to stick to it. Such a solder joint can give bad contacts.
If the items soldered together were moved during the cooling of the solder, the soldering can be bad as well.
If the soldering looks mechanical solid, it usually is electrical in order. Solderings can become bad after a couple of years if they are mechanically stressed too much. If the soldered component heats up a lot, it's soldering can become bad as well after a couple of years. Those failures can be visual inspected.
I am unsure about the position of the SCL and SDA signals on the lpc bus of a 1.6 xbox.
I do know (from hearing) that a 1.6 xbox switches the power off in case of a frag. If you connect the eeprom reader, the xbox normally frags. You can avoid that by leaving the pc site disconnected until the xbox booted (into an error screen or wathever)
You can find the SCL and SDA signals on several chips of the xbox. The eeprom chip has them, the clock chip has them and the pic microcontroller has them. If you check the pins of those chips and the lpc bus holes, you should measure zero ohms between them. If you have that, you know you are on the right holes.
To know which pins of the chip are SCL and SDA, you can google for the datasheets of that chip. I recently saw a good pin description of the pic microcontroller in the xbox on this forum.
Maybe the LPC holes of a 1.6 mobo are color coded, but thoses of my 1.0 and 1.1 surely aren't.
So, I would suggest you check the holes to make sure they are the SCL and SDA signals.
If you switch the xbox on, with the reader connected, your xbox should frag.
(this is the only case where a frag is a good sign.)
If you disconnect the pc connector before switching things on, make sure you connect a gnd wire between the pc case and the xbox shielding. Leave that wire connected all the time. As the xbox supply cable doesn't have an earth wire, there might be a voltage difference between the xbox shielding and the pc shielding. The wire will ensure they both have the same voltage.
regards.