Just a note to say thanks to this post.
Here is my situation if it helps... IHAS 124 Drive
After initial flash with LT max burns on 4x and OPC on were fine. After 5/6 my backups started failing verification on the 50% mark.. Tried tweaking but all came out the same. Followed funksoulbrothers guide and my next burn was perfect.. BUT my second burn failed.... Rebooted PC (power cycle drive) and 3rd burn was ok again.. Fingers crossed I have my solution but KUDOS for this post as I was having a stack of coasters..
Here is my working method (to date)
Reboot PC
Disable Antivirus
Clear OPC History EEPROM
Write Speed 4x
Media Verbatim MKM-003 (India)
OPC OFF
Turn On Force HyperTuning
Turn Off Online HyperTuning
Turn On Smart Burn
Turn Off OverSpeed
Success
QUOTE(funksoulbrother @ Nov 15 2011, 03:00 PM)

I had a similar problem. I burned about 10 discs and all of them gave good-great results in KProbe, then all of a sudden I was getting coaster after coaster. That was with MKM-003-00 discs made in Singapore and all from the same spindle.
I use these settings now, recommended by Lightning UK (the creator of ImgBurn): -
1. Clear OPC history using EEPROM Utility and power cycle the drive.
2. Enable Smart Burn and Force Hyper Tuning.
3. Disable Over Speed Writing and Online Hyper Tuning.
4. Disable OPC in ImgBurn.
5. Burn at 4X.
In your case, as you just started using a new spindle of discs, it could be a bad batch, but give those settings a try anyway.