Sorry Zamboni, but I deleted the ISO already, so I cant replicate the error. For what it's worth, it's the NBA2K3 ISO (in case you or someone else who wants to test this may have it). I havent had this error again, but I've only transferred one more in the meantime, which had no problems. FWIW, it will not autoupdate properly (hangs in the middle), but if I hit the update button again, it seems to do it properly (just takes a while, which is why I thought it hung).
Oh, I forgot to mention (sorry guys, but it would have solved some of your problems), but if your ISO file has any other extension other than ".iso" (all lower case), the program will just throw the whole ISO across (ie. it will not decompress the ISO). Zamboni, I think you already realized this, so this is just a confirmation.
Jiggy.
ps. Maybe you could put an option in to automatically call the directory "PxGameX" (where X is the next number) so it's automatically manageable by PxHDDLoader? It's not a big deal, but what the hey...